Status:
UNKNOWN
The Effect of Post-surgical Chlorhexidine Mouth Washing on the Sub-gingival Periodontal Microbiome A Pilot Study
Lead Sponsor:
Rambam Health Care Campus
Conditions:
Periodontitis
Subgingival Plaque
Eligibility:
All Genders
18-99 years
Brief Summary
Prospective applicants who conform with inclusion and exclusion criteria will be accepted into the study and sign a consent form. Visit 1: After initial screening a case report form (CRF) will be fil...
Detailed Description
Microbial identification: periodontal samples will be collected by the GeneFiX™ Saliva DNA Microbiome Collection Device (Isohelix). DNA Extraction - the MagMAX Microbiome Ultra Nucleic Acid Isolation ...
Eligibility Criteria
Inclusion
- Signed Informed Consent Form
- Age ≥18 years
- Scheduled for periodontal/dental surgery without pre- and/or post-surgical antibiotic therapy
Exclusion
- Pre-existing conditions that may affect the microbiome, including diagnoses of diabetes, malignancy, alcoholism, previous head and neck radiation therapy
- Pregnancy and breast-feeding
- Chronic medications that are known to affect periodontal tissues such as Ca channel blockers and phenytoin
- Antibiotic therapy within the previous 6 weeks
- Mouthwash therapy within the previous 2 weeks
- Known allergy to CM or any of its constituents
- Smoking \>10 cigarettes/day
Key Trial Info
Start Date :
February 3 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 25 2024
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT05355740
Start Date
February 3 2023
End Date
June 25 2024
Last Update
March 30 2023
Active Locations (2)
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1
Rambam Health Care Campus
Haifa, Israel, 3109601
2
Rambam Health Care Campus
Haifa, Israel, 31096