Status:
RECRUITING
FGF23 and Cardiovascular Damage in Anemia With an Without Chronic Kidney Disease.
Lead Sponsor:
Maimónides Biomedical Research Institute of Córdoba
Collaborating Sponsors:
Fondo de Investigacion Sanitaria
Conditions:
Fibroblast Growth Factor 23
Anemia
Eligibility:
All Genders
18-85 years
Brief Summary
Anemia is associated with cardiovascular disease. Iron deficiency is usually induced in chronic kidney disease (CKD). In clinical studies, an inverse association between serum levels of iron and fibro...
Detailed Description
1 Study populations 1.1) Study in patients with iron deficiency anemia with normal renal function. The study will be carried out in the serum samples of patients. All patients will be provided with th...
Eligibility Criteria
Inclusion
- Hemoglobin \< 11g/dl
- Serum ferritin \< 100 ng/ml or transferrin saturation index \< 20%
Exclusion
- Weight \< 50 Kg or BMI \< 17
- Acute bleeding \> 500 ml, within 72 hours before study inclusion
- Proliferative hematologic disease. Hemochromatosis
- Active infections within 30 days before study inclusion
- Systemic inflammatory illness
- Human immunodeficiency virus (HIV), Hepatitis C virus (HCV) or Hepatitis B virus (HBV) infection
- Iron active treatment
- Blood transfusion in the last 90 days before inclusion.
- Cardiovascular hospitalization 30 days before study inclusion
- Anticoagulant treatment with coumarins
- Chronic liver disease
- Immunosuppressive therapy
- Erythropoiesis stimulating agents treatment, radiotherapy or chemiotherapy within 30 days before inclusion
- Scheduled major surgery during study period
- Pregnancy or lactation
- Drugs addiction
- Participation in others clinical trials.
Key Trial Info
Start Date :
October 18 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2025
Estimated Enrollment :
401 Patients enrolled
Trial Details
Trial ID
NCT05356325
Start Date
October 18 2021
End Date
July 1 2025
Last Update
February 7 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Hospital Universitario Reina Sofia
Córdoba, Spain, 14004