Status:
RECRUITING
Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)
Lead Sponsor:
University of Texas Southwestern Medical Center
Conditions:
Anesthesia
Propofol Adverse Reaction
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
The purpose of this study is to evaluate the hemodynamics and adverse event profile in comparison between two treatment arms, one using an admixture of propofol and etomidate at a ratio by volume of 2...
Detailed Description
Procedural/Surgical anesthesia induction, administration and maintenance with propofol combined with etomidate is commonly used in routine clinical practice in patient with compromised cardiopulmonary...
Eligibility Criteria
Inclusion
- Adult patients (age ≥18 years old)
- Having endoscopic procedure at CUH with anesthesia
- ASA 3 or above
- Ejection Fraction test result available
Exclusion
- Known allergies or adverse reactions to study drugs or study drug components or preservatives
- Patient refusal
- Clinician refusal
- Documented cognitive impairments precluding subject ability to consent for themselves unless a surrogate documented legally acceptable decision maker consents for patient participation
- Prisoner or incarcerated or patients held by law enforcement officials in custody
- Pregnancy or patient refusal for pregnancy testing or screening (standard UTSW policy and protocol requires pregnancy testing for appropriate patients prior to anesthesia)
Key Trial Info
Start Date :
September 19 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2026
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT05358535
Start Date
September 19 2022
End Date
March 1 2026
Last Update
October 20 2025
Active Locations (1)
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1
Clements University Hospital
Dallas, Texas, United States, 75390