Status:
UNKNOWN
Effect of Probiotics on Oral Candida Among Denture Wearers
Lead Sponsor:
Hams Hamed Abdelrahman
Conditions:
Oral Candida Albicans Infection
Eligibility:
All Genders
40+ years
Phase:
NA
Brief Summary
Forty-eight denture wearers with detectable levels of candida colonization without clinical symptoms will be randomly allocated into two groups: probiotics and placebo. All patients will take a daily ...
Eligibility Criteria
Inclusion
- Detectable levels of Candida in palatal mucosa without clinical symptoms of active candidiasis.
- Completely edentulous arches with newly formed denture .
- Patients with controlled hypertension, and diabetes will be included in this study as they are considered very common problems in the targeted population.
Exclusion
- Inability to understand/ follow the experimental procedures,
- Administration of topic or systemic antifungal or antibacterial agents in the previous 60 days.
- Consumption of probiotics.
- GITdisorders.
- Heartdisease.
- Diseases that significantly influence immunity such as; kidney problems, head and neck cancer, or radiotherapy, AIDS, or immunosuppressive therapy.
- Clinical manifestations of oral candidiasis.
Key Trial Info
Start Date :
May 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 30 2023
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT05358743
Start Date
May 1 2022
End Date
January 30 2023
Last Update
January 12 2023
Active Locations (1)
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1
Alexandria Faculty of Dentistry
Alexandria, Egypt