Status:

COMPLETED

Evaluation of the Effect of Adding Dexamethasone to 2% Lidocaine

Lead Sponsor:

Jamia Millia Islamia

Conditions:

Pulpitis - Irreversible

Eligibility:

All Genders

18-59 years

Phase:

NA

Brief Summary

This randomized, double-blind clinical trial aimed at the evaluation of the effect of adding dexamethasone to 2% lidocaine, given as inferior alveolar nerve block in the endodontic management of sympt...

Eligibility Criteria

Inclusion

  • absence of any periapical radiolucency on radiographs, except for a widened periodontal ligament
  • active pain in a mandibular molar
  • prolonged response to cold testing with an ice stick and an electric pulp tester
  • vital coronal pulp on access opening and ability to understand the use of pain scales

Exclusion

  • a history of known or suspected drug abuse
  • history of active peptic ulcer within the preceding 12 months
  • history of bleeding problems or anticoagulant use within the last month
  • known allergy, sensitivity, or contraindications to any opioid or nonopioid analgesic including aspirin or NSAIDs
  • patients who had taken NSAIDs within 12 h before administration of the study drugs
  • patients who were pregnant or breast-feeding

Key Trial Info

Start Date :

February 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 25 2021

Estimated Enrollment :

124 Patients enrolled

Trial Details

Trial ID

NCT05361291

Start Date

February 1 2020

End Date

August 25 2021

Last Update

May 5 2022

Active Locations (1)

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Faculty of Dentistry, Jamia MIliia Islamia

New Delhi, India, 110025