Status:

COMPLETED

Remote Ischemic Preconditioning and Acute Kidney Injury in HTX

Lead Sponsor:

Heinrich-Heine University, Duesseldorf

Conditions:

Heart Transplantation

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Postoperative Acute Kidney Injury (AKI) is a common complication after heart transplantation (HTX) affecting outcome of patients. Remote ischemic preconditioning (RIPC) is an intervention that showed ...

Detailed Description

Postoperative Acute Kidney Injury (AKI) is a common complication after heart transplantation (HTX) affecting outcome of patients. Anesthesia- and surgery-related factors, but also hemodynamic instabil...

Eligibility Criteria

Inclusion

  • \- adult patients (\>18 years) undergoing HTX

Exclusion

  • Acute myocardial infarction up to 7 days before surgery
  • age younger than 18 years
  • pre-existing AKI
  • previous kidney transplantation
  • chronic kidney disease with a glomerular filtration rate less than 30ml/min
  • pregnancy
  • peripheral vascular disease affecting the upper limbs
  • hepato-renal syndrome
  • drug therapy with sulfonamide or nicorandil

Key Trial Info

Start Date :

June 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 30 2024

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT05364333

Start Date

June 1 2022

End Date

April 30 2024

Last Update

May 1 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University Hospital Duesseldorf

Düsseldorf, North Rhine-Westphalia, Germany, 40225