Status:
TERMINATED
Platelet Reactivity With Fentanyl, Morphine, or no Narcotic
Lead Sponsor:
Corewell Health South
Conditions:
Fentanyl
Platelet Reactivity
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
The goal is to determine whether fentanyl and morphine have similar effects in reducing aspirin's effect upon platelets in emergency department patients with chest discomfort. Morphine has been shown ...
Detailed Description
Patients presenting to the emergency department with chest discomfort who are being administered aspirin will be offered enrollment in this study. At the time of their zero and two hour troponin we wi...
Eligibility Criteria
Inclusion
- Adult Emergency Department patients undergoing 0 and 2 hour troponin testing
- administered aspirin within 30 minutes of the initial blood draw.
- patient presented via private vehicle
- provide informed consent
- over the age of 18
Exclusion
- Patients not expected to get a 2 hour troponin;
- patients already on aspirin, clopidogrel, or stronger anti-coagulants;
- patients who arrived via EMS (Emergency Medical Services) given it can be difficult to find the run reports to determine whether patient received fentanyl in the pre-hospital period;
- pregnant patients;
- patients on chronic narcotics;
- patients already once enrolled in this study,
- inability to provide consent in English
Key Trial Info
Start Date :
August 31 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 18 2025
Estimated Enrollment :
21 Patients enrolled
Trial Details
Trial ID
NCT05367336
Start Date
August 31 2022
End Date
February 18 2025
Last Update
May 21 2025
Active Locations (1)
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1
Spectrum Health Lakeland
Saint Joseph, Michigan, United States, 49085