Status:
COMPLETED
Antibiotics, Gastric Bypass, and the Microbiome
Lead Sponsor:
Medical College of Wisconsin
Conditions:
Obesity, Morbid
Hypertension
Eligibility:
All Genders
18-70 years
Phase:
PHASE1
Brief Summary
This study randomizes patients to two commonly used peri-procedural antibiotics after gastric bypass with the pre and post-operative collection of stool samples, to identify significant differences in...
Detailed Description
Eligible patients will be reviewed to meet inclusion criteria. Patients will be approached for enrollment at their pre-operative clinic appointment. If patients agree, consent will be signed. Demogra...
Eligibility Criteria
Inclusion
- Patients who are approved for a primary RYGB at MCW's bariatric surgery program as treatment for morbid obesity and obesity-associated co-morbidities. Patients will be eligible who are: 1.) female or male 2.) 18-70 years of age, 3.) hypertensive
Exclusion
- Patients are ineligible if they: 1.) have a diagnosis of cirrhosis, 2.) are taking antibiotics, probiotics, or immune modulating medications for one month prior to or after surgery, 3.) have a history of bowel resections, inflammatory bowel disease and/or celiac disease, 4.) have a life-threatening reaction to penicillin/cephalosporins or clindamycin.
Key Trial Info
Start Date :
July 18 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 9 2020
Estimated Enrollment :
23 Patients enrolled
Trial Details
Trial ID
NCT05367479
Start Date
July 18 2018
End Date
January 9 2020
Last Update
May 10 2022
Active Locations (1)
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1
Froedtert Hospital
Milwaukee, Wisconsin, United States, 53226