Status:

COMPLETED

Salivary Bmp-2 Levels & Radiographic Measurement Of Bone Density at Extracted Tooth

Lead Sponsor:

Postgraduate Medical Institute, Lahore

Conditions:

Bone Injury

Eligibility:

All Genders

18-25 years

Phase:

PHASE4

Brief Summary

Salivary Bmp-2 Levels \& Radiographic Measurement Of Bone Density were evaluated At Extracted Tooth Socket in patients With \& Without topical Application Of Simvastatin

Detailed Description

Objective: The objective of this study was to compare: 'The salivary BMP-2 levels in the experimental and the control groups with and without topical simvastatin application on wound of extracted too...

Eligibility Criteria

Inclusion

  • Both male and female patients with permanent dentition, age (18 years to 25 years) were considered.
  • Patients undergoing extraction of maxillary or mandibular Pre molars for orthodontic procedure.
  • Teeth which required only simple non surgical extraction only under local anesthesia.

Exclusion

  • Subjects taking antibiotics or non-steroidal anti inflammatory drugs (NSAIDS) within one week.
  • Patients with oral mucosal lesions (leukoplakia, erythroplakia, lichen planus).
  • Patients with oral carcinoma.
  • Patients with xerostomia.
  • Previous history of radiotherapy or chemotherapy
  • Patient with known hypersensitivity to anti inflammatory drugs.
  • Diabetic patients.
  • Pregnant and lactating patients.
  • Patients with social habits such as cigarette smoking and alcohol consumption.
  • Teeth radiographically involved in any abscess/cyst/granuloma.
  • Teeth requiring open surgical transalveolar extraction.

Key Trial Info

Start Date :

December 16 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 5 2022

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT05369091

Start Date

December 16 2020

End Date

January 5 2022

Last Update

May 11 2022

Active Locations (1)

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1

Dental Department of Lahore General Hospital.

Lahore, Punjab Province, Pakistan