Status:
ACTIVE_NOT_RECRUITING
Hypertension in Young Adults Trial
Lead Sponsor:
University of California, San Francisco
Conditions:
Hypertension
Eligibility:
All Genders
18-40 years
Phase:
PHASE2
Brief Summary
This is a pilot randomized controlled trial which will test the effect of 3 different anti-hypertensive agents and 3 different strategies of engaging young adults in home blood pressure monitoring on ...
Eligibility Criteria
Inclusion
- 18-40 years of age
- Diagnosis of hypertension or receiving anti-hypertensive therapy OR Has clinical BP readings \>130/80 mmHg that would meet the definition of hypertension and have home BP readings \>=125/80 mmHg
Exclusion
- are or are planning to become pregnant, due to inability to take multiple classes of anti- hypertensive agents
- are marginally housed, due to concerns regarding routine follow-up
- are actively participating in a different interventional trial that may affect blood pressure
- are unwilling to consent to participate
- institutionalized individuals or prisoners
- are actively abusing illicit drugs or alcohol
- have a history of poor or doubtful compliance (e.g., frequently missed appointments)
- have cognitive impairment prohibiting participation in the study
- History of allergy to any of the randomized medications
- Serum potassium \>5.5 meq/L at the screening visit
- BP \> 160/100 mmHg in clinic (stage II hypertension), regardless of whether patient is on therapy
- eGFR \< 30 mL/min/1.73 m2
Key Trial Info
Start Date :
April 15 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2027
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT05370599
Start Date
April 15 2022
End Date
May 1 2027
Last Update
March 27 2025
Active Locations (1)
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1
University of California San Francisco
San Francisco, California, United States, 94143