Status:

UNKNOWN

Performance of Novel Bed Side Scores as Predictors of Hospital Outcome in Acute Exacerbation of Chronic Obstructive Pulmonary Disease Among Women; Cohort Study

Lead Sponsor:

Assiut University

Conditions:

COPD Exacerbation

Eligibility:

All Genders

35+ years

Brief Summary

* Assess predictors of mortality in COPD exacerbation between men and women. * Evaluate the clinical outcomes in acute exacerbation of COPD in women. * Evaluate the validity of new scoring systems ( N...

Eligibility Criteria

Inclusion

  • Patients with AECOPD leading to hypoxemia, hypercapnia and respiratory acidosis with pH \< 7.35 and PaCO2 \> 45 mm of Hg will be admitted to the respiratory intensive care unit (ICU) for NIV or the ward will be eligible for inclusion and not in need for mechanical ventilation

Exclusion

  • Requirement for emergency intubation.
  • Other contraindications to NIPPV including cardiac or respiratory arrest; nonrespiratory organ failure (eg, severe encephalopathy, severe gastrointestinal bleeding, hemodynamic instability with or without unstable cardiac angina); facial surgery or trauma; upper-airway obstruction; inability to protect the airway and/or high risk of aspiration; and inability to clear secretions.(6)
  • Age \< 35 years.

Key Trial Info

Start Date :

July 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

April 1 2025

Estimated Enrollment :

203 Patients enrolled

Trial Details

Trial ID

NCT05370664

Start Date

July 1 2022

End Date

April 1 2025

Last Update

June 15 2022

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