Status:
UNKNOWN
Impact of N-acetylcysteine Infusion and Intralipid Infusion on Myocardial Injury in Aluminum Phosphide Toxicity
Lead Sponsor:
Assiut University
Conditions:
Myocardial Injury
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Assess impact of ILE and NAC in morbidity and mortality when used as adjuvant therapy to routine management of acute ALP poisoning.
Detailed Description
Aluminum phosphide (ALP) is one of the solid fumigant pesticides. In Egypt, ALP is extensively used to protect grains against insects and rodents. It is available in the form of tablets known as "grai...
Eligibility Criteria
Inclusion
- Presentation with symptomatic acute ALP poisoning.
- History of exposure including reliable identification of the compound based on the container brought by patient's relatives.
- The suggestive clinical manifestations following shortly after a single exposure to ALP.
Exclusion
- Co-ingestion or exposure to other substances in addition to ALP.
- Patients had major medical conditions (e.g., cardiovascular disease, renal or hepatic failure).
- Patients received treatment in any hospital or medical center before admission - other than emergency department of Assiut University Hospital.
Key Trial Info
Start Date :
May 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2025
Estimated Enrollment :
58 Patients enrolled
Trial Details
Trial ID
NCT05370729
Start Date
May 1 2022
End Date
May 1 2025
Last Update
May 11 2022
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