Status:
COMPLETED
Quercetin's Effect on Bone Health and Inflammatory Markers
Lead Sponsor:
Kennesaw State University
Conditions:
Osteoporosis, Postmenopausal
Eligibility:
FEMALE
45-75 years
Phase:
NA
Brief Summary
Quercetin is a plant-based flavonoid that is naturally found in many fruits and vegetables, and is considered to be a potent antioxidant with several expected health benefits such as anti-inflammatory...
Detailed Description
Quercetin is a plant-based flavonoid that is naturally found in many fruits and vegetables such as onions, apples, berries, green tea, and red wine and is currently an FDA approved supplement. Quercet...
Eligibility Criteria
Inclusion
- Clinically defined as postmenopausal (absence of menstrual cycle for 12 months without contraceptives or the surgical removal of the reproductive organs)
- Activity levels ranging from sedentary to recreationally active were included in the study.
Exclusion
- Hyper- or hypothyroidism (uncontrolled)
- Hyper- or hypoparathyroidism
- Gastrointestinal disorders
- Renal disorders
- Orthopedic disorders
- Rheumatological disorders
- Immunological disorders
- Type I diabetic
- Being treated with any diabetic injectable medication(s).
- Taking any non-steroidal, steroidal, or anti-inflammatory drugs
- Currently, or in the past 1 month, were consuming daily calcium
- Currently, or in the past 1 month, were consuming more than 5,000 IU's of vitamin D supplements
- Taking any anti-obesity medications
- Taking any osteoporotic medication(s)
- Taking any long-term antibiotics.
- Current smoker
- Diagnosed with osteoporosis, or if their BMD was equal to, or fell below -2.50 via dual x-ray absorptiometry (DXA) during visit 1
- Involved in heavy resistance training
- Began a new unaccustomed exercise routine during the 90-days
- Allergies to food(s) rich in QUE such as onions, apples, or berries; or if they were unwilling to avoid quercetin-containing foods.
Key Trial Info
Start Date :
August 27 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 27 2020
Estimated Enrollment :
33 Patients enrolled
Trial Details
Trial ID
NCT05371340
Start Date
August 27 2019
End Date
April 27 2020
Last Update
May 12 2022
Active Locations (1)
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1
Kennesaw State University
Kennesaw, Georgia, United States, 30144