Status:

UNKNOWN

Plasma microRNA Levels and Some Cytokines Expression in Patients With ITP Primary Immune Thrombocytopenic Purpura (ITP)

Lead Sponsor:

Sohag University

Conditions:

Primary Immune Thrombocytopenia

Eligibility:

All Genders

18-90 years

Brief Summary

Immune thrombocytopenia (ITP) is an autoimmune disease characterized by low platelet counts with or without mucocutaneous bleeding (McMillan, 2007). Like the majority of autoimmune diseases, ITP is an...

Detailed Description

In recent years the critical role of miRNAs has been established in many diseases, including autoimmune disorders. Immune thrombocytopenic purpura (ITP) is a predominant autoimmune disease, in which a...

Eligibility Criteria

Inclusion

  • ITP patients

Exclusion

  • 1- Secondary causes of ITP as systemic lupus erythematosus (SLE), viral infections (HIV, hepatitis B or C infections) 2- Other underlying medical diseases that may cause thrombocytopenia as:
  • malignancy
  • megaloblastic anemia
  • aplastic anemia
  • lymphoproliferative disorders
  • liver disease
  • renal impairment
  • pregnancy 3-Organomegally and/or lymphadenopathy. 4-Recent history of vaccination. 5-Recent evidence of bacterial infection.

Key Trial Info

Start Date :

May 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

September 1 2023

Estimated Enrollment :

2 Patients enrolled

Trial Details

Trial ID

NCT05371743

Start Date

May 1 2022

End Date

September 1 2023

Last Update

April 12 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Sohag University

Sohag, Egypt, 82733