Status:
UNKNOWN
High Spinal Anesthesia and the Incidence of Delirium After Cardiac Surgery
Lead Sponsor:
University of Manitoba
Conditions:
Post-Operative Confusion
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This is a feasibility study to determine if enough patients undergoing elective or urgent cardiac surgery, can be enrolled in a study where patients are randomized to receive high spinal anesthesia as...
Detailed Description
Intervention Patients will be randomized to either general anesthesia (GA) or HSA + GA. 1. Spinal group: will receive high spinal anesthesia with hyperbaric bupivacaine (0.3 to 0.6 mgs/kg) + preserv...
Eligibility Criteria
Inclusion
- Adult (\>18 years old) patients
- Undergoing elective or urgent cardiac surgical procedures with cardiopulmonary bypass
Exclusion
- Contraindications to spinal anesthesia such as active anticoagulation, clopidogrel within 7 days of surgery, ticagrelor within 3 days of surgery and all other contraindications to lumbar puncture
- Pre-existing psychiatric diagnoses such as schizophrenia or manic-depressive disorder
- Complex aortic surgery (\> hemi-arch repair, descending thoracic surgery)
- Difficult airway requiring an awake intubation
- BMI \> 50
Key Trial Info
Start Date :
May 2 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2024
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT05374356
Start Date
May 2 2022
End Date
June 30 2024
Last Update
June 28 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
St. Boniface Hospital
Winnipeg, Manitoba, Canada, R2H 2A6