Status:
COMPLETED
The Effect of Increasing Current or Pulse Duration on Patient Movement and Intraoperative Transcranial Electric Stimulation Motor Evoked Potential Amplitude
Lead Sponsor:
Insel Gruppe AG, University Hospital Bern
Conditions:
Surgery
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Transcranial electric stimulation (TES) motor evoked potential (MEP) monitoring is standard during surgery risking motor system injury. The stimuli are typically 5-pulse trains with a 4 ms interstimul...
Detailed Description
Transcranial electric stimulation (TES) motor evoked potential (MEP) monitoring is standard during surgery risking motor system injury. The stimuli are typically 5-pulse trains with a 4 ms interstimul...
Eligibility Criteria
Inclusion
- Informed Consent signed by the subject
- The patient has a supra- or infra-tentorial lesion requiring surgery
- The patient is undergoing neurosurgery with the use of Intraoperative Monitoring (IOM) during surgery to protect functional tissue
- The patient is older than 18 years
Exclusion
- No need for Intraoperative Monitoring (IOM)
- Vulnerable subjects (pregnant women, pregnant, impaired consciousness)
- People who do not want to participate in the study
- Emergency procedures in which no consent was obtained before the operation
- Multiple surgeries on the same patient
- Preoperative non-affected arm motor deficit (MRC \<5), that is to say, no motor deficit of the arm ipsilateral to the surgery
- Inhalational anesthesia
- Persisting neuromuscular blockade
Key Trial Info
Start Date :
August 10 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2024
Estimated Enrollment :
31 Patients enrolled
Trial Details
Trial ID
NCT05375669
Start Date
August 10 2022
End Date
November 1 2024
Last Update
April 1 2025
Active Locations (1)
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1
Dep. of Neurosurgery, Bern University Hospital
Bern, Switzerland, 3010