Status:
UNKNOWN
Povidone Iodine Nasal Irrigation and Gargling to Reduce Viral Load in Asymptomatic Patients With COVID-19
Lead Sponsor:
Ruijin Hospital
Conditions:
2019 Novel Coronavirus Infection
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The emergence of a novel coronavirus(SARS-CoV-2) in late 2019 has resulted in a global epidemic of the infectious condition COVID-19. Since March 2022, the Omicron mutant has caused widespread transmi...
Detailed Description
The purpose of the study is to evaluate if using nasal irrigation and gargling with PVP-I and hypertonic saline solution, can improve the negative conversion rate of SARS-CoV-2 nucleic acid on day 10 ...
Eligibility Criteria
Inclusion
- Patients nucleic acid testing positive for COVID-19.
- Diagnose as asymptomatic patients infected by COVID-19, and receive medical observation at a Fang Chang Hospital.
- Be able to understand this study, willing to participate in, and sign the informed consent form.
- Commit to follow the research procedures and cooperate in the implementation of the whole process research.
- Can communicate with researchers through smart phones.
Exclusion
- The nucleic acid test result of novel coronavirus has always been negative after entering the Fang Chang Hospital.
- patients who have history of nasal surgery, or current use of nasal saline irrigation or other intranasal medications.
- Patients with thyroid diseases , respiratory diseases or other serious basic diseases.
- Allergy to iodine.
- Participation in another prospective COVID related research project(clinical trial).
- Pregnancy or lactation
- Patients with immune deficiency (such as patients with malignant tumors, organ or bone marrow transplantation, patients with AIDS, and those taking immunosuppressive drugs within 3 months before screening).
- Other patients considered unsuitable by the investigator to participate in this study
Key Trial Info
Start Date :
April 16 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 31 2022
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT05375773
Start Date
April 16 2022
End Date
October 31 2022
Last Update
May 24 2022
Active Locations (1)
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1
Ruijin Hospital,Shanghai Jiaotong University school of medicine
Shanghai, Shanghai Municipality, China