Status:

COMPLETED

Evaluate the Long Term Safety and Efficacy of DWP16001 add-on to Metformin in Patients With T2DM Inadequately Controlled on Metformin

Lead Sponsor:

Daewoong Pharmaceutical Co. LTD.

Conditions:

T2DM (Type 2 Diabetes Mellitus)

Eligibility:

All Genders

19-80 years

Phase:

PHASE3

Brief Summary

A Multi-center, Open-label, Extension study to Evaluate the long term Safety and Efficacy of DWP16001 add-on to metformin in Patients with type 2 diabetes mellitus inadequately controlled on metformin

Eligibility Criteria

Inclusion

  • Participated in the prior phase 3 study (Protocol No: DW\_DWP16001302) for meeting the inclusion criteria and completed the study
  • Voluntarily decided to participate in the extension study and provided a written consent on the consent form

Exclusion

  • Withdrawn from the prior phase 3 study (Protocol No: DW\_DWP16001302) or expected of having safety issue if taking part in the study in the judgment of the investigator
  • Subjects with the following diseases or signs:
  • Diabetic ketoacidosis
  • Moderate to severe renal impairment (estimated glomerular filtration rate \[eGFR\] \< 60 mL/min/1.73 m2
  • Females who are pregnant or breast-feeding, or subjects who do not agree to the use of appropriate contraceptive methods throughout the study
  • Subjects must agree to one of the following appropriate contraceptive methods for subjects or their partners:
  • ① Either surgical sterilization (vasectomy, etc.) or insertion of an intrauterine device (copper loop, intrauterine hormone-containing system), or
  • ② A physical barrier method combined with either systemic hormonal contraceptives or spermicide, or
  • ③ Use of male condom combined with either cervical cap or diaphragm Determined to be ineligible for the study by the investigator, besides the above

Key Trial Info

Start Date :

May 25 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 16 2022

Estimated Enrollment :

159 Patients enrolled

Trial Details

Trial ID

NCT05376969

Start Date

May 25 2021

End Date

May 16 2022

Last Update

October 25 2022

Active Locations (1)

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Daewoong pharmatceutical

Seoul, South Korea