Status:

COMPLETED

Intervention Effectiveness on the Neurocognitive Functioning of Children and Adolescents With Neurofibromatosis Type 1

Lead Sponsor:

Virginia Commonwealth University

Conditions:

Neurocognitive Deficit

Mental Health Impairment

Eligibility:

All Genders

6-16 years

Phase:

NA

Brief Summary

Children with neurofibromatosis are more likely to have difficulties related to their psychological and neurocognitive functioning (e.g., more likely to have depression, have social difficulties, be d...

Detailed Description

Neurofibromatosis type 1 (NF1) is a chronic illness that is typically diagnosed during childhood and is associated with a variety of medical, psychological, and neurocognitive symptoms. NF1 is a genet...

Eligibility Criteria

Inclusion

  • Patients are eligible if they are English-speaking children and adolescents between the ages of 6 to 16 years diagnosed with NF who are currently followed by the Pediatric NF Clinic at VCU. Patients are eligible if they currently have a diagnosis of ADHD or do not have a diagnosis of ADHD.
  • At least one parent/caregiver must be actively involved in the patient's care and able to complete study-related questionnaires at baseline, 3-, and 6-months; and the exit interview at 7-months. Parents are eligible if they if they are English-speaking adults 18+ years old and self-identify as the parent or guardian of the patient.

Exclusion

  • Presence of serious, chronic comorbid condition (asthma and ADHD are not exclusionary criteria), presence of serious cognitive/learning impairment (e.g., down syndrome, moderate to severe intellectual disability or developmental disability), temporary foster care or residential care placement with no known plans to remain with foster parent for at least one year, presence of serious ongoing psychiatric disorder that prevents patient or family member from accurately completing questionnaires, and/or family anticipates moving in the next 12 months.
  • No subject will be excluded on the basis of gender or ethnicity.

Key Trial Info

Start Date :

May 13 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 5 2023

Estimated Enrollment :

38 Patients enrolled

Trial Details

Trial ID

NCT05377008

Start Date

May 13 2022

End Date

May 5 2023

Last Update

September 22 2023

Active Locations (1)

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1

Children's Hospital of Richmond at Virginia Commonwealth University

Richmond, Virginia, United States, 23219