Status:
RECRUITING
The Effect of Hyperoxia on Ventilation During Recovery From General Anesthesia
Lead Sponsor:
Stanford University
Conditions:
Ventilatory Depression
Postoperative Respiratory Failure
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
In this randomized-controlled trial the investigators will examine the effect of oxygen supplementation on the recovery of breathing for 90 minutes in the immediate post-anesthesia period starting fro...
Detailed Description
In a pilot randomized-controlled trial (NCT04723433) the investigators found that hyperoxia, compared with standard O2 supplementation, enhanced ventilation, as estimated by the fraction of time at a ...
Eligibility Criteria
Inclusion
- American Society of Anesthesiologists (ASA) physical status I-III
- Body mass index (BMI) less than 40 kg/m2
- Scheduled to undergo robotic-assisted radical laparoscopic nephrectomy or prostatectomy.
Exclusion
- Patients with a diagnosis of chronic obstructive pulmonary disorder (COPD), severe neurological, cardiopulmonary, psychiatric, or untreated thyroid disorder
- Chronic pain condition that is being treated with opioids
- Patients with a hematocrit lower than 30% at the end of surgery, or those with an excessive blood loss, requiring transfusion of blood products during surgery.
Key Trial Info
Start Date :
October 4 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05379673
Start Date
October 4 2022
End Date
December 1 2026
Last Update
May 16 2025
Active Locations (1)
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1
Stanford University School of Medicine
Stanford, California, United States, 94305