Status:
COMPLETED
Efficacy Long-term Dietary Nitrate Consumption to Plasma Nitrite Conversion
Lead Sponsor:
Wake Forest University
Conditions:
Cardiovascular Diseases in Old Age
Eligibility:
All Genders
40-80 years
Phase:
NA
Brief Summary
The objective of this study was to determine the chronic effects of beetroot juice supplementation on the acute (90-minute post nitrate consumption) efficacy of converting dietary nitrate to plasma ni...
Eligibility Criteria
Inclusion
- Middle and Older (40-80 year-old) men and women
- Body mass index between 18.5 - 30.0 kg/m2
- Able to provide own transportation to study testing visits
- Able to consume study beverages
- Able to speak and read English
Exclusion
- Tobacco user (smoke or chew), including e-cigarettes
- Known conditions of: diabetes mellitus (type 1 or 2), atrophic gastritis, hypo- or hyperthyroidism, gout, history of kidney stones, history of hypotension, cardiovascular disease, chronic obstructive pulmonary disease, inflammatory bowel diseases, impaired liver or kidney function
- Current or recent (last 3 months) treatment for cancer
- Current use of the following medications: Phosphodiesterase type 5 inhibitors, nitroglycerin or nitrate preparations, proton pump inhibitors, medication for hypothyroidism, antacid and heartburn medications
Key Trial Info
Start Date :
September 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2019
Estimated Enrollment :
13 Patients enrolled
Trial Details
Trial ID
NCT05380167
Start Date
September 1 2017
End Date
May 1 2019
Last Update
May 25 2022
Active Locations (1)
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1
Wake Forest University
Winston-Salem, North Carolina, United States, 27109