Status:

COMPLETED

Serotype Distribution in Hospitalized Adult With Pneumococcal Community Acquired Pneumonia in France

Lead Sponsor:

Institut National de la Santé Et de la Recherche Médicale, France

Conditions:

Pneumonia

Pneumococcal Infections

Eligibility:

All Genders

18+ years

Brief Summary

CAP'Hospi is an observational, multicentric study in France which primary objective is to describe the proportion of Community Acquired Pneumonia due to serotypes included in PCV20 among adults hospit...

Eligibility Criteria

Inclusion

  • Adults 18 years of age or older
  • Admission to hospital for at least 24 hours
  • Suspicion of community-acquired pneumonia at admission defined as the association of: Radiologic findings consistent with pneumonia (eg, pleural effusion, increased pulmonary density due to infection and/or alveolar infiltrates \[multilobar, lobar, or segmental\] containing air bronchograms), AND The presence of ≥2 of the following signs or symptoms: Fever (oral temperature \>38°C or tympanic temperature \>38.5°C) in the 24 hours preceding admission; Hypothermia (\<35.5°C measured by a healthcare provider) in the 24 hours preceding admission ; Chills or rigors ; Pleuritic chest pain ; New or worsening cough ; Sputum production ; Dyspnea (shortness of breath); Tachypnea (respiratory rate \>20/min) ; Malaise ; Abnormal auscultatory findings suggestive of pneumonia (rales or evidence of pulmonary consolidation)
  • Written informed consent from the patient

Exclusion

  • Suspicion of tuberculosis
  • Individuals placed under judicial protection
  • Individuals who refuse the transfer of biological samples to the USA
  • Patient developing signs and symptoms of pneumonia after having been hospitalized for 48 hours or more
  • Pregnancy

Key Trial Info

Start Date :

May 9 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

February 6 2025

Estimated Enrollment :

1017 Patients enrolled

Trial Details

Trial ID

NCT05380193

Start Date

May 9 2022

End Date

February 6 2025

Last Update

May 15 2025

Active Locations (5)

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Page 1 of 2 (5 locations)

1

CHU Rennes

Rennes, Brittany Region, France, 35000

2

Hopital de la Croix Rousse, Hospices Civils de Lyon

Lyon, France, 69004

3

Hôpital Cochin

Paris, France, 75014

4

Hôpital Bichat

Paris, France, 75018