Status:

COMPLETED

Association Between Erythroferron and Perioperative Hemoglobin Levels in Patient Undergoing Heart Valve Surgery

Lead Sponsor:

Yonsei University

Conditions:

Postoperative Anemia

Eligibility:

All Genders

20+ years

Brief Summary

In patients undergoing cardiac surgery, perioperative anemia is an important factor in surgical recovery. In addition to the low preoperative hemoglobin level, the delayed recovery of the postoperativ...

Eligibility Criteria

Inclusion

  • Patients older than 20 years
  • undergoing elective valvular heart surgery

Exclusion

  • Emergency operation
  • Co-operation with other surgeries
  • Patients with cardiogenic shock or ventricular-assist device (eg. ECMO, IABP)
  • Patients requiring mechanical ventilator care in preoperative period
  • Patient with severe chronic kidney disease (GFR(CKD-EPI) \<30ml/min/1.73m2)
  • Patients with preoperative infection status (Eg. Sepsis)
  • Patients with acute bleeding status
  • Hemoglobin concentration below 10g/dL
  • Disease directly affecting hematopoiesis (eg. Leukemia, myeloma, aplastic anemia)
  • Uncompensated liver cirrhosis, acute hepatitis, alcoholics
  • Patients who participated in other clinical studies that could affect prognosis
  • Patients who cannot understand the informed consent (eg. Foreigner)

Key Trial Info

Start Date :

June 23 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 15 2025

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT05384054

Start Date

June 23 2022

End Date

September 15 2025

Last Update

October 2 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Yonsei University Health System, Severance Hospital

Seoul, South Korea