Status:

UNKNOWN

Enhanced Versus Extended Preoperative Antibiotic Prophylaxis Regimens for Retrograde Intrarenal Surgery in High Infectious Risk Patients

Lead Sponsor:

Mansoura University

Conditions:

Renal Stone

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

In the available literature, there is a lack the risk categorization of infectious complications after RIRS with subsequent recommendation as regard to AP in different risk patients. Therefore this st...

Detailed Description

Retrograde intrarenal surgery (RIRS) has gained a wide popularity in the management of renal stones due to tremendous technological advancements over the last years. According to the current guideline...

Eligibility Criteria

Inclusion

  • Ability to give informed consent.
  • Age ≥18 years.
  • Renal stone \<20 mm in which RIRS is recommended.
  • High susceptibility of post-procedural infectious complications by one or more of the followings: - Positive preoperative urine culture within 12 weeks of the planned intervention. -Indwelling ureteral stents for more than 4 weeks. -Diabetes mellitus.

Exclusion

  • Solitary kidney.
  • Chronic kidney disease.
  • Pregnant.
  • Have received antibiotics within 7 days prior to enrollment.

Key Trial Info

Start Date :

May 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2023

Estimated Enrollment :

280 Patients enrolled

Trial Details

Trial ID

NCT05384197

Start Date

May 1 2022

End Date

July 1 2023

Last Update

November 14 2022

Active Locations (1)

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1

Mansoura Urology and Nephrology Center

Al Mansurah, Outside U.S./Canada, Egypt, 35516