Status:

NOT_YET_RECRUITING

Analysis of the Prognostic Role of Epigenetic Biomarkers in Relation to the Motor Decline in Parkinson's Disease

Lead Sponsor:

Istituto Nazionale di Ricovero e Cura per Anziani

Conditions:

Parkinson Disease

Eligibility:

All Genders

65+ years

Brief Summary

BioGenParkinson is an observational, prospective cohort study evaluating biomarkers of Parkinson's Disease (PD) progression in community-dwelling subjects aged 65 years or more, consecutively referrin...

Detailed Description

The objective of the BioGenParkinson study is the evaluation of the prognostic accuracy of epigenetic, genetic and protein biomarkers in relation to Parkinson's Disease (PD) motor symptoms progression...

Eligibility Criteria

Inclusion

  • PD at Hoehn and Yahr stage ≤3
  • MMSE test ≥24 score

Exclusion

  • MMSE score \< 24
  • Severe cardiovascular diseases (including congestive heart failure NYHA=4, acute coronary syndrome, stroke)
  • History of traumatic brain injury, previous deep brain surgery
  • Current substance or alcohol abuse
  • Reduced life expectancy less than six months

Key Trial Info

Start Date :

May 30 2024

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 30 2026

Estimated Enrollment :

103 Patients enrolled

Trial Details

Trial ID

NCT05384522

Start Date

May 30 2024

End Date

January 30 2026

Last Update

March 5 2024

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