Status:

COMPLETED

Protein Kinase N1 Level in Patients Undergoing Cardiac Surgery

Lead Sponsor:

Zhongnan Hospital

Conditions:

Acute Kidney Injury

Extracorporeal Circulation; Complications

Eligibility:

All Genders

18+ years

Brief Summary

Acute kidney injury (AKI) is one of the most frequent major complications in patients undergoing cardiac surgery. CSA-AKI is independently related to increased perioperative mortality, increased hospi...

Detailed Description

Acute kidney injury (AKI) is one of the most frequent major complications in patients undergoing cardiac surgery. The incidence of cardiac surgery-associated AKI (CSA-AKI) varies from 5% to 42% and is...

Eligibility Criteria

Inclusion

  • Patients (≥18 years old) underwent on-pump cardiac surgery
  • admitted to ICU immediately after surgery

Exclusion

  • Patients younger than 18 years
  • with prior AKI
  • end-stage kidney disease
  • need for chronic hemodialysis
  • pregnant patients
  • unable to give written consent for participation

Key Trial Info

Start Date :

July 22 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 14 2021

Estimated Enrollment :

110 Patients enrolled

Trial Details

Trial ID

NCT05386940

Start Date

July 22 2019

End Date

March 14 2021

Last Update

May 23 2022

Active Locations (1)

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Zhongnan Hospital of Wuhan University

Wuhan, Hubei, China, 430000