Status:

COMPLETED

The Effect of Mandibular Advancement Devices on Markers of Cardiovascular Health in Obstructive Sleep Apnea Patients

Lead Sponsor:

University of Alberta

Conditions:

Obstructive Sleep Apnea

Eligibility:

All Genders

18-70 years

Brief Summary

Obstructive sleep apnea (OSA) is a type of disordered breathing defined by the repetitive obstruction of airflow during sleep due to upper airway collapse. Each obstructive event contributes to decrea...

Detailed Description

In OSA the obstruction of breathing can be either partial (hypopnea) or complete (apnea), and each obstructive event contributes to decreased blood oxygen, or hypoxia. Sleep disordered breathing and n...

Eligibility Criteria

Inclusion

  • Between ages of 18-70
  • Diagnosed with Obstructive Sleep Apnea and prescribed with Mandibular Advancement Device
  • No medical history of cardiovascular, pulmonary, renal diseases

Exclusion

  • Any known cardiovascular, respiratory or pulmonary disease
  • Have a history of smoking regularly in past 6 months
  • Pre-existing symptomatic non-respiratory sleep disorder (restless leg syndrome, chronic insomnia)
  • if more than 50% of their observed apneas are due to sleep apnea

Key Trial Info

Start Date :

July 11 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 9 2024

Estimated Enrollment :

4 Patients enrolled

Trial Details

Trial ID

NCT05387122

Start Date

July 11 2021

End Date

September 9 2024

Last Update

September 19 2024

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University of Alberta

Edmonton, Alberta, Canada, T6G 2R3