Status:

UNKNOWN

DSUVIA in Patients With SCD VOC Present in the ED

Lead Sponsor:

Jason Wilson

Conditions:

Sickle-Cell Disease With Crisis

Eligibility:

All Genders

18+ years

Brief Summary

This is an observational study to improve the treatment of patients with Sickle Cell Disease Vaso-Occlusive Crisis by administering pain medications more quickly after the patient arrives in the emerg...

Detailed Description

Patients with SCD VOC may present to the ED after oral home medications fail to relieve acute pain. Patients with SCD VOC may require parenteral analgesia for pain relief but, upon arrival to the ED t...

Eligibility Criteria

Inclusion

  • Age \>= 18
  • Known history/self-reported history of Sickle Cell Disease
  • Participant has self-described sickle cell related pain
  • Patient has attempted to utilize oral opioid pain medications in the last 24 hours

Exclusion

  • Unable to provide informed consent to participate in the study, such as a mental condition rendering the participant unable to understand the nature, scope, and possible consequences of the study
  • Participant has a temperature of \> 100.4 F
  • Participant has heart rate \> 120
  • Participant has systolic blood pressure \< 90
  • Clinical provider or investigator states that patient has "Acute Chest Syndrome"
  • Participant unlikely to comply with protocol as determined by Investigator
  • Clinically relevant cardiovascular, hepatic, neurological, endocrine, or other major systemic disease making implementation of the protocol or interpretation of the study results difficult or that would put the participant at risk by participating in the study
  • Persistent significant or severe infection, either acute or chronic
  • No prior oral opioid use for SCD VOC pain control
  • Participation in this study within the past 30 days.

Key Trial Info

Start Date :

March 30 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2023

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT05388188

Start Date

March 30 2022

End Date

December 1 2023

Last Update

May 24 2022

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Tampa General Hospital

Tampa, Florida, United States, 33606