Status:

COMPLETED

Study of Prostate Perfusion Before Embolization in Patients With Symptomatic Prostate Adenoma

Lead Sponsor:

Centre Hospitalier Universitaire de Nīmes

Conditions:

Prostate Cancer

Eligibility:

MALE

18+ years

Phase:

NA

Brief Summary

Over the last 5 years, prostate embolization has developed as a treatment for symptomatic prostate adenoma. This long, complex procedure is effective in 80% of cases. Currently there are no means of b...

Detailed Description

The hypothesis is that there are two types of prostate vascularization in patients with symptomatic prostate adenoma: * prostates mainly vascularized by large caliber prostate arteries with high flow...

Eligibility Criteria

Inclusion

  • Patients with symptomatic benign prostatic hypertrophy (prostate volume \> 50, IPSS \>7, QoL\>2) or patients catheterized after acute retention of urine with failed catheterization.
  • Creatinine clearance \> 30 mL/min for one of the two Cockcroft-Gault/MDRD equations)
  • Adult patients (≥18 years).
  • Patients with an indication for prostate embolization.
  • Patient with free and informed consent.
  • Patient who have signed the consent form.
  • Patient affiliated or beneficiary of a health insurance plan.

Exclusion

  • Hypersensitivity to the active substance or to one of the excipients of the iodized contrast medium.
  • Severe renal impairment with renal function \<30mL/min.
  • Contraindication to prostate embolization (aorto-iliac bypass)
  • Patient participating in research defined as Category 1 Research Involving Human Subjects.
  • Patient in an exclusion period as determined by another study.
  • Patient under court protection, guardianship or curatorship.
  • Patient unable to give consent.
  • Patient for whom it is impossible to give informed information.

Key Trial Info

Start Date :

May 12 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 19 2024

Estimated Enrollment :

45 Patients enrolled

Trial Details

Trial ID

NCT05389202

Start Date

May 12 2022

End Date

January 19 2024

Last Update

March 10 2025

Active Locations (1)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (1 locations)

1

Nîmes University Hospital

Nîmes, Gard, France, 30029