Status:
RECRUITING
Potassium Citrate and Crystal Light Lemonade
Lead Sponsor:
Northwestern University
Conditions:
Kidney Stone
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
To define the effect of crystal light, potassium citrate, or both on urinary stone risk factors in patients with a history of stone and hypocitraturia/low pH
Eligibility Criteria
Inclusion
- Men and women between age 18-80 years
- Willing to follow experimental protocol
- Willing to complete 24-hour urine collections (three total)
- Willing to sign the informed consent form
- Completed Litholink Collection with blood work with results
- a. hypocitraturia OR aciduria i. Hypocitraturics must meet definition of \< 450 mg/day for men \< 550 mg/day for women.
- b. Low urine pH must be less than 5.6 c. potassium, BUN, creatinine, eGFR and hemoglobin A1c within normal limits
Exclusion
- Patients with severe hypocitraturia \< 200 mg/day (men or women)
- Patients with hyperkalemia, uncontrolled diabetes, chronic kidney disease, adrenal insufficiency, delayed gastric emptying (or drug induced delayed gastric emptying), peptic ulcer disease, or active UTI
- Patients with distal renal tubular acidosis or medication induced RTA (e.g. carbonic anhydrase inhibitor, topiramate)
- Members of vulnerable patient populations
- Allergies to ingredients in crystal light
- Patients lacking decisional capacity
Key Trial Info
Start Date :
August 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 31 2025
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT05389995
Start Date
August 1 2022
End Date
October 31 2025
Last Update
April 27 2025
Active Locations (1)
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1
Northwestern University
Chicago, Illinois, United States, 60611