Status:
RECRUITING
REward SYSTem in Autism Spectrum Disorder and Addictive Disorder
Lead Sponsor:
University Hospital, Tours
Collaborating Sponsors:
INSERM UMR-1253, Tours, France
Conditions:
Autism Spectrum Disorder
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
An MRI Study in Subjects with Autism Spectrum Disorder and Subjects with Food Addictive Disorder compared to healthy volunteers.
Detailed Description
An MRI Study in Subjects with Autism Spectrum Disorder and Subjects with Food Addictive Disorder compared to healthy volunteers, where pathophysiology common to both disorders, based on a dysfunction ...
Eligibility Criteria
Inclusion
- Arm A ˗ Concerning ASD patients: Adult carrying the diagnosis of ASD (DSM-5, ADOS, ADI-R criteria)
- Arm B ˗ Concerning FAD patients: Adult diagnosed with FA presenting with food addiction (DSM-5, YFAS 2.0, BES \>= 18 criteria).
- Arm C ˗ Concerning healthy volunteers : Adult with no neurological and psychiatric history , absence of progressive somatic pathologies or with vital risk.
- For all participants:
- Age greater than or equal to 18 years old
- Without intellectual delay (IQ \> 70).
- Able to understand and apply the instruction when an active task is proposed, according to the estimate of the investigator.
- Free, express, informed and written consent of the participant.
- Participant affiliated to a social security scheme
Exclusion
- Neuromotor disorders.
- Visual disturbances not corrected or incompatible with MRI.
- Known epilepsy.
- Current substance use disorder with emotional distress/significant impact on functional outcome
- Rare genetic syndrome.
- Contraindications to MRI (other than body circumference)
- For women of childbearing age: negative urine or blood pregnancy test
- Person subject to a measure of judicial protection (safeguard of justice, curatorship, guardianship or family authorization)
Key Trial Info
Start Date :
July 27 2023
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 27 2027
Estimated Enrollment :
78 Patients enrolled
Trial Details
Trial ID
NCT05391113
Start Date
July 27 2023
End Date
January 27 2027
Last Update
December 6 2024
Active Locations (3)
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1
Center-Val de Loire Region Autism Resource Center
Tours, France, 37044
2
University Addictology Service, Liaison Team and Addictology Care
Tours, France, 37044
3
University Hospital, Medical Imaging Service
Tours, France, 37044