Status:

UNKNOWN

Characteristics of Peripheral Blood Lymphocyte Subsets in Children With PNS

Lead Sponsor:

Nanfang Hospital, Southern Medical University

Conditions:

Lymphocyte Disorder

Nephrotic Syndrome

Eligibility:

All Genders

Up to 18 years

Brief Summary

The etiology and precipitating factors of PNS remain unclear. Dysfunction of immunologic function is a classic theory of the pathogenesis of PNS. This study was aimed at investigating the characterist...

Detailed Description

As a common type of nephrosis in children, primary nephrotic syndrome (PNS) is a clinical syndrome characterized by a heavy proteinuria, hypoalbuminemia, edema, and hyperlipidemia, caused by increased...

Eligibility Criteria

Inclusion

  • age \<18 years old
  • first PNS episode or PNS in remission
  • no history of corticosteroid or immunosuppressor use in the four weeks prior to disease occurrence

Exclusion

  • Subjects with infantile (or congenital) nephrotic syndrome (NS), secondary NS, glomerulonephritis, or systemic disease were excluded.

Key Trial Info

Start Date :

May 30 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

August 31 2022

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT05392244

Start Date

May 30 2022

End Date

August 31 2022

Last Update

May 26 2022

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