Status:
UNKNOWN
Respiratory Muscle Fatigue at Different Breathing Modes
Lead Sponsor:
Aalborg University
Conditions:
Healthy
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
The study aims at investigating if time to respiratory muscle fatigue and metabolism are influenced by the pressure wave form mode applied during resistive breathing.
Detailed Description
In healthy subjects fitted with a nasogastric double balloon catheter and breathing at a resistance, the investigators will measure time to failure, Borg ratings, VO2, VCO2, flow, esophageal-, gastric...
Eligibility Criteria
Inclusion
- Healthy men or women
- Age ≥18 and ≤60 years
- BMI ≥ 20 and ≤30
Exclusion
- Drug addiction defined as the use of cannabis, opioids or other drugs
- Previous and present neurologic (e.g. ataxia), musculoskeletal (e.g. muscular dystrophy) or mental illnesses (e.g. schizophrenia)
- History of mechanical ventilation, COVID-19 with respiratory complications, lung cancer
- Part of lung resected
- Presence of dyspepsia/heart-burn/abdominal pain
- Presence of esophageal varices
- Presence of liver disease
- Presence of esophageal hernia
- Pregnancy
- Failure to comply with transcranial magnetic stimulation adult safety screen
- History of epilepsy, metal implants in head or jaw
- Acute or chronic lung diseases, e.g. asthma, COPD, bronchitis etc.
- Lack of ability to cooperate
Key Trial Info
Start Date :
October 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2022
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT05393115
Start Date
October 1 2021
End Date
December 1 2022
Last Update
May 26 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Mathias Krogh Poulsen
Aalborg, Danmark, Denmark, 9220