Status:

UNKNOWN

Field Evaluation of Two Topically Applied Insect Repellent Products Containing IR3535 Against Mosquitos in Louisiana

Lead Sponsor:

Louisiana State University Health Sciences Center in New Orleans

Conditions:

Bites and Stings

Eligibility:

All Genders

18-55 years

Phase:

NA

Brief Summary

To determine the efficacy and duration of protection of two topically applied insect repellent products at preventing landing by mosquitos. The study will follow the EPA Product Performance Test Guide...

Detailed Description

A single-site field setting study using healthy volunteers to test two insect repellent product formulations (lotion, and wipe) against mosquitos. Subjects will have repellent applied to one lower li...

Eligibility Criteria

Inclusion

  • Able and willing to give fully informed consent;
  • Male or female;
  • Aged 18 to 55 years;
  • Consider themselves to be in good general health, and specifically:
  • Not aware of having any cardiovascular or respiratory disorder (whether active or inactive)
  • No previous anaphylaxis
  • Not aware of having a compromised immune system
  • Non-smokers or willing to refrain for 24 hours prior to and during each test;
  • Willing to undergo a mosquito attraction test (putting an arm into a cage of mosquitos)
  • Able to speak and understand English
  • Able to stand outside for periods of at least 5 minutes at a time
  • Able to understand and comply with the study procedures, including:
  • Willing to complete mosquito landing/aspirating training
  • Able to withstand exposing the lower leg to mosquitos for periods of at least 5 minutes at a time
  • Able to operate an aspirator

Exclusion

  • Participated in any other intervention study in the previous 3 months
  • Participated in a biting insect test as part of the current study in the previous 72 hours
  • Employees, managers, and spouses of employees of the LSU and of the study Sponsor (LivFul, Inc.)
  • Students of the Study Director or any other LSU faculty/researchers involved in the study
  • Individuals suspected or known to be sensitive or allergic to, or phobic of, mosquito bites
  • Women who are pregnant, nursing or intending to become pregnant during the course of the study
  • Individuals with localized skin disorders or problems affecting the legs (such as eczema, psoriasis, or atopic dermatitis) or open cuts or scrapes
  • Individuals with known or suspected allergy or sensitivity to the test product or any of its ingredients, or any insect repellent products
  • Individuals who are not attractive to mosquitos during mosquito attractiveness test
  • Individuals who have signs or symptoms related to COVID-19, have tested positive for COVID-19 within the last 15 days, or have had contact (within 6 feet for a total of 15 minutes or more) with someone who has tested positive for COVID-19 in the last 14 days.

Key Trial Info

Start Date :

June 11 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 10 2022

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT05394597

Start Date

June 11 2021

End Date

June 10 2022

Last Update

May 27 2022

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Louisiana State University, Department of Entomology

Baton Rouge, Louisiana, United States, 70803