Status:
RECRUITING
Optical Correction and Visual Functions of Adults With Amblyopia
Lead Sponsor:
Centre for Eye and Vision Research
Collaborating Sponsors:
The Hong Kong Polytechnic University
University of Waterloo
Conditions:
Amblyopia
Eligibility:
All Genders
18-39 years
Phase:
NA
Brief Summary
Amblyopia is a developmental anomaly resulting from abnormal visual experiences in early life. Amblyopia causes reduced visual acuity in the absence of a pathology. Adult sensory systems are believed ...
Eligibility Criteria
Inclusion
- 18-39 (inclusive) years of age
- Anisometropic amblyopia (difference of ≥0.50D spherical equivalent or ≥1.50D astigmatism between eyes) or mixed mechanism amblyopia (strabismus and anisometropia)
- Best corrected visual acuity (BCVA) in the amblyopic eye of 0.3 logMAR to 1.0 logMAR (inclusive)
- BCVA in the non-amblyopic eye of 0.1 logMAR or better, and an interocular VA difference of 2 logMAR lines or more
- Difference of 1.00D or more between current refractive correction and study prescription
- Good general health
Exclusion
- Other pathological ocular anomalies known to cause reduced visual acuity
- Presbyopia (based on amplitude of accommodation)
- Inability to tolerate prescribed refractive correction in spectacles (e.g., due to aniseikonia)
- Contraindication to cycloplegic eye drops
- Currently under amblyopia treatment/therapy
- Inability to comprehend test instructions and/or provide consent
- Eccentric fixation
- \>-6.00DS of myopia in either eye with spectacles
- Bilateral amblyopia
- Presence of amblyopia that is not due to strabismus and/or anisometropia
- Presence of (current or previous) psychiatric, visual, or neurological disorders
Key Trial Info
Start Date :
June 13 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 31 2027
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT05394987
Start Date
June 13 2022
End Date
May 31 2027
Last Update
June 14 2024
Active Locations (2)
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1
University of Waterloo
Waterloo, Ontario, Canada, N2L 3G1
2
Centre for Eye and Vision Research Limited
Hong Kong, Guangdong, Hong Kong, 00000