Status:

COMPLETED

Uterine Elastography: a Potential Predictor of Embryo Transfer Success

Lead Sponsor:

Reproductive Medicine Associates of New Jersey

Conditions:

Infertility, Female

Eligibility:

FEMALE

18-45 years

Brief Summary

To determine if the mean elasticity value (measured in kilopascals, kPa) of a patient's endometrium, myometrium and cervix in a sonographically normal appearing uterus predict frozen embryo transfer (...

Eligibility Criteria

Inclusion

  • Female patients, 18yo-45yo, presenting for ultrasound the day prior to embryo transfer
  • Patients planning to undergo single embryo transfer (SET) of a euploid embryo by Preimplantation genetic testing for aneuploidy (PGT-A)
  • Uterine evaluation prior to transfer (saline sonogram or hysteroscopy) within 1 year
  • Egg recipients

Exclusion

  • Gestational carriers
  • BMI \> 35
  • Diagnosis of a uterine anomaly
  • History of uterine surgery, excluding polypectomy, c-section, D\&C
  • Communicating hydrosalpinx
  • Transfer of an embryo of unknown ploidy status or embryos of undetermined safety
  • Surgically retrieved sperm
  • Embryos that were cryopreserved on day 7 of development
  • Poor quality embryos defined by modified Gardner grading criteria used in the embryology lab
  • Sonographically abnormal appearing uteri, including distortions from leiomyomas and thin endometrium

Key Trial Info

Start Date :

June 15 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 1 2023

Estimated Enrollment :

162 Patients enrolled

Trial Details

Trial ID

NCT05397912

Start Date

June 15 2022

End Date

September 1 2023

Last Update

February 7 2025

Active Locations (1)

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Reproductive Medicine Associates of New Jersey

Basking Ridge, New Jersey, United States, 07920