Status:
RECRUITING
A Natural History Study of Metabolic Sizing in Health and Disease
Lead Sponsor:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions:
Metabolic Disorders
Cancer
Eligibility:
All Genders
2-99 years
Brief Summary
Background: Scientists have long used simple measures (such as height and weight) to estimate how much a person s body uses food (calories) as energy, as commonly called the metabolic rate. But metab...
Detailed Description
Study Description: This study will examine the relationships between comprehensively measured resting energy expenditure (REE), body composition, and body surface area (BSA) in a wide range of health...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- In order to be eligible to participate in this study, an individual must meet all the following criteria for their cohort:
- Cohort 1 - Healthy Volunteers
- Male or female, aged \>=2 years
- In good general health as evidenced by medical history
- Cohort 2 - Patients
- Male or female, aged \>=2 years
- Diagnosed with diseases thought to alter metabolism or body composition (such as weight loss or gain, diabetes, renal disease, obesity, cancer, etc.) or taking medications thought to alter metabolism or body composition.
- EXCLUSION CRITERIA:
- An individual who meets any of the following criteria will be excluded from participation in this study:
- Participants over 200 kg due to the weight limit of the equipment.
- Presence of any implanted device that would interfere with measurements.
- Any moderate to severe limitations in mobility that would impede participation
- Hemoglobin less than 10 g/dL (in participants who would have blood drawn for research purposes)
- Participants with dietary allergies, intolerances or eating patterns that would preclude them from consuming metabolic meals.
- Participants unwilling or unable to give informed consent.
- Participants with any other significant physical, medical, or psychiatric limitations, illness or conditions that may preclude them from completing the majority of the tests in this study per the discretion of the PI.
Exclusion
Key Trial Info
Start Date :
October 25 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2031
Estimated Enrollment :
2000 Patients enrolled
Trial Details
Trial ID
NCT05398783
Start Date
October 25 2022
End Date
July 1 2031
Last Update
January 2 2026
Active Locations (1)
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1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892