Status:
COMPLETED
Supine Positioning for Graft Attachment After Descemet Membrane Endothelial Keratoplasty
Lead Sponsor:
University Eye Hospital, Freiburg
Conditions:
Fuchs' Endothelial Dystrophy
Eligibility:
All Genders
18-100 years
Phase:
NA
Brief Summary
This randomized controlled trial evaluates the efficacy and safety of postoperative supine head positioning on graft attachment after Descemet membrane endothelial keratoplasty in patients with Fuchs'...
Detailed Description
In Descemet membrane endothelial keratoplasty (DMEK), an air or gas bubble is inserted in the anterior chamber of the eye to keep the ultrathin endothelial corneal graft attached to the patients own c...
Eligibility Criteria
Inclusion
- Diagnosis of advanced Fuchs' endothelial corneal dystrophy (FECD)
- Indication for corneal endothelial transplantation (Descemet Membrane Endothelial Keratoplasty - DMEK)
Exclusion
- Other corneal diseases (i.e. corneal scars, corneal dystrophies except FECD, corneal inflammation / infection)
- Regular use of drugs potentially affecting the cornea (i.e. amiodarone, chloroquine, triptan, isotretinoin, use of contact lenses in past four weeks, anesthetic eye drops)
- Diabetes mellitus with endorgan complications)
- Lack of fixation during corneal tomography
- Bedridden
Key Trial Info
Start Date :
May 23 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 23 2023
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT05399095
Start Date
May 23 2022
End Date
May 23 2023
Last Update
July 25 2023
Active Locations (1)
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1
Medical Center - University of Freiburg, Eye Hospital
Freiburg im Breisgau, Baden-Wurttemberg, Germany, 79106