Status:
COMPLETED
the Oncogenic Potential of Salivary miRNA-93 and miRNA-412-3P in Oral Lichen Planus Patients
Lead Sponsor:
Moataz Mahmoud
Collaborating Sponsors:
Cairo University
Conditions:
Oral Lichen Planus
Oral Cancer
Eligibility:
All Genders
40-70 years
Brief Summary
Assessment The oncogenic potential of salivary microRNA-93 and microRNA-412-3p in oral lichen planus
Detailed Description
Oral lichen planus is one of the most common prevalent muco-cutaneous chronic diseases. The disease is definitely auto-immune type .Despite having idiopathic etiology, many risk factors can be conside...
Eligibility Criteria
Inclusion
- Both genders with age range from 40 to 70 years.
- Clinically diagnosed and histologically confirmed as having symptomatic OLP.
- Patients who agree to sign a written consent after understanding the nature of the study
Exclusion
- -Systemic and/or local systemic drug therapy within the last 3 months prior to the start of the study
- Patients on steroidal or non-steroidal anti-inflammatory drugs (NSAIDs) for at least the last 6 months
- Patients on Retinoid, green tea supplements or another natural products therapy
- Patients with already diagnosed malignant lesion/lesions
- Pregnant or Lactating females
- Vulnerable groups as prisoners, mentally disabled, etc…
Key Trial Info
Start Date :
January 15 2023
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 30 2023
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT05400057
Start Date
January 15 2023
End Date
September 30 2023
Last Update
October 10 2023
Active Locations (2)
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1
Facuty of Dentistry, CairoU
Cairo, Egypt, 00202
2
Facuty of Dentistry, CairoU
Cairo, Egypt, 002