Status:
COMPLETED
Gag-layer in the Urothelium of the Human Upper Urinary Tract
Lead Sponsor:
Aarhus University Hospital
Collaborating Sponsors:
Ferring Ventures
Conditions:
Bladder Cancer
Renal Cancer
Eligibility:
All Genders
18+ years
Brief Summary
Urothelial carcinomas of the lower and upper urinary tract can be considered "twin diseases". Much of the current clinical decision-making surrounding Upper Tract Urothelial Carcinoma (UTUC) is extrap...
Detailed Description
This study will include patients either undergoing radical nephrectomy or radical cystectomy. After organ removal during surgery a biopsi (1x1 cm) will be collected from the ureter and the renal pelvi...
Eligibility Criteria
Inclusion
- Bladder cancer or renal cell carcinoma
- Ability to understand and sign informed consent form
Exclusion
- Previous history of cancer
- Immune suppressing medication
- Treatment with local or systemic steroids (\< 3 months prior to enrollment)
- Treatment with antibiotics due to urinary tract infection or pyelonephritis (\< 3 months prior to enrollment)
- Previous radiation therapy of the pelvic floor
- Ureteric stent
- Dilatation of the upper urinary tract detected on imaging
- Dilatation of the upper urinary tract detected on imaging
Key Trial Info
Start Date :
December 1 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2022
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT05400291
Start Date
December 1 2021
End Date
December 31 2022
Last Update
June 1 2023
Active Locations (1)
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1
Aarhus University Hospital
Aarhus, Denmark, 8200