Status:
RECRUITING
Deep Brain Stimulation for Visuomotor Function in Parkinson's Disease
Lead Sponsor:
VA Office of Research and Development
Conditions:
Parkinson's Disease
Eligibility:
All Genders
Brief Summary
Inability to align and refocus the eyes on the objects at different depths, i.e., vergence impairment, frequently affects the quality of life in patients with Parkinson's disease. Our study aims to un...
Detailed Description
The victims of very common condition Parkinson's disease (PD) are known to have tremor, rigidity, and slow movements. PD, in addition to its effects on human movements, also affects many other aspect ...
Eligibility Criteria
Inclusion
- Parkinson's disease with bilateral STN DBS
- Availability of pre-operative MR images (with a T1-weighted, gradient-echo sequence) and ability to get post-operative MRI or CT scans
- Hoehn and Yahr stage 2-4 when off medication, and a stable antiparkinsonian medication regimen and DBS parameter settings
Exclusion
- Previous surgical therapy for Parkinson's disease (other than DBS)
- Dementia
- Clinically significant untreated depression or anxiety
- Clinical features suggestive of atypical parkinsonism
Key Trial Info
Start Date :
October 4 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2026
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT05400499
Start Date
October 4 2022
End Date
July 1 2026
Last Update
January 7 2026
Active Locations (1)
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1
Louis Stokes VA Medical Center, Cleveland, OH
Cleveland, Ohio, United States, 44106-1702