Status:
COMPLETED
Effect of Oral Zinc and Vitamin E Supplementation on Short-term Postoperative Outcomes in Cardiac Surgery Patients.
Lead Sponsor:
Shahid Beheshti University
Collaborating Sponsors:
Kerman University of Medical Sciences
Conditions:
Heart Surgery
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Cardiac surgery can cause oxidative stress due to ischemia-reperfusion. Using antioxidants during perioperative period may help improve this condition. Vitamin E and zinc have antioxidant effects. In ...
Detailed Description
Cardiac surgery is a life-saving invasive procedure that may often be associated with significant postoperative complications. Cardiac surgery can cause oxidative stress due to ischemia-reperfusion. T...
Eligibility Criteria
Inclusion
- Patients who are candidates for open heart surgery (coronary artery bypass grafting)
Exclusion
- Frequent use of multivitamin, zinc, vitamin E, vitamin C, omega-3 supplements over the past month
- Active cancer, chronic rheumatic disease, ESRD, liver cirrhosis, severe infection (WBC\> 12000 mm3) before surgery
- Continued use of corticosteroids or NSAIDs for two weeks prior to admission (except A.S.A)
Key Trial Info
Start Date :
June 6 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 3 2023
Estimated Enrollment :
78 Patients enrolled
Trial Details
Trial ID
NCT05402826
Start Date
June 6 2022
End Date
January 3 2023
Last Update
January 5 2023
Active Locations (1)
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1
Shafa Hospital, Kerman University of Medical Sciences
Kerman, Iran