Status:
UNKNOWN
Epithelial Mesenchymal Transition and Periodontitis
Lead Sponsor:
University of Baghdad
Conditions:
Periodontitis
Periodontal Diseases
Eligibility:
All Genders
18+ years
Brief Summary
Periodontitis is a chronic inflammatory disease results is destruction of the attachment apparatus of the teeth and ultimately tooth loss. Epithelial-mesenchymal transition (EMT) is a process compris...
Detailed Description
Periodontitis is a highly prevalent inflammatory disease affecting the attachment apparatus of the teeth, leading to progressive destruction of periodontal ligament and resorption of alveolar bone whi...
Eligibility Criteria
Inclusion
- Diagnosed with generalized periodontitis, unstable, no risk factor
- Selected site should be indicated for surgical treatment by modified Widman flap in posterior area and these sites must exhibit periodontal pockets ≥ 5mm or pockets ≥ 4mm with BOP
- Plaque index score \< 10%
- Never smoker or former smoker
- Not currently using systemic or local antimicrobials (at least in the last three months)
- Not currently using a mouth rinse
- In good general health with no evidence of any systemic disease
- Willing to consent
Exclusion
- Have history of systemic disease e.g., diabetes mellitus
- Periodontal treatment in the last 6 months
- Current participation in other clinical trials
- Pregnant women
- Current smoker
- Not willing to sign the consent form
Key Trial Info
Start Date :
July 12 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
August 30 2022
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT05403164
Start Date
July 12 2021
End Date
August 30 2022
Last Update
June 3 2022
Active Locations (1)
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1
College of Dentistry, University of Baghdad
Baghdad, Iraq