Status:

RECRUITING

Marathon of Hope Cancer Centres Network Study for Ontario (MOHCCN-O)

Lead Sponsor:

University Health Network, Toronto

Collaborating Sponsors:

Princess Margaret Hospital, Canada

Ontario Institute for Cancer Research

Conditions:

Breast Cancer

Colorectal Cancer

Eligibility:

All Genders

18+ years

Brief Summary

The Marathon of Hope Cancer Centres Network (MOHCCN) is a national network of cancer centres that pursue collaborative cancer research in precision medicine (an emerging approach for disease treatment...

Detailed Description

The purpose of this study is to use evolving technologies such as genomics and artificial intelligence to study cancer so that the right treatment can be given to the right patient, at the right time....

Eligibility Criteria

Inclusion

  • Patients with histological and/or cytological confirmation of blood or solid tumor malignancies. For tumour types where pre-surgical biopsy is not routinely performed to confirm a pathologic diagnosis of cancer, patients may consent to this protocol, but eligibility must be confirmed after pathology is finalized demonstrating presence of malignancy
  • All patients must be able to satisfy the required minimum data elements for the 15k gold standard cohort through:
  • Already existing data that satisfies the minimal requirements of a gold standard case (refer to Table 1)
  • Have sufficient biospecimens (tumor and/or blood samples) available for more comprehensive molecular and immunophenotypic characterization
  • Patients who do not satisfy the required minimum data elements but would like to participate, maybe requested to donate blood and undergo a fresh biopsy if the archived Formalin-fixed paraffin-embedded (FFPE) samples are not available, or in cases where a fresh tumor biopsy is deemed necessary for molecular profiling.
  • Participating patients must agree to share their anonymized clinical and genomic data

Exclusion

  • None.

Key Trial Info

Start Date :

June 23 2022

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 1 2026

Estimated Enrollment :

500 Patients enrolled

Trial Details

Trial ID

NCT05403177

Start Date

June 23 2022

End Date

October 1 2026

Last Update

February 3 2025

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Kingston Health Sciences Centre

Kingston, Ontario, Canada, K7L 2V7

2

Ottawa Health Research Institute

Ottawa, Ontario, Canada, K1Y 4E9

3

Princess Margaret Cancer Centre

Toronto, Ontario, Canada, M5G2M9

Marathon of Hope Cancer Centres Network Study for Ontario (MOHCCN-O) | DecenTrialz