Status:
COMPLETED
Study of Structural and Functional Brain Connectivity Changes in ALS (CoALS-II)
Lead Sponsor:
Dartmouth-Hitchcock Medical Center
Conditions:
Amyotrophic Lateral Sclerosis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study will try to understand the difference in brain structure between ALS patients and healthy people of similar age. ALS is a condition affecting the nervous system with disruption of the brain...
Detailed Description
Participants and healthy controls will be consented into the study. After consent, details including age, duration of disease, ALSFRS score, and grip strength will be collected. Participants will be t...
Eligibility Criteria
Inclusion
- Based on El Escorial Criteria we will select Probable or Definite ALS.
- Healthy controls age matched to ALS patients
- Subjects should be able to lie down in a scanner and undergo an hour-long MRI study
- Subjects should be able to understand instructions, provide consent and perform a hand task while inside the scanner
Exclusion
- Unable to undergo MRI due to any reason
- Age \<18
- ALS patients having high aspiration risk
- Patients having cognitive limitations which prevents them from understanding the study requirements, providing consent or perform tasks inside the scanner.
Key Trial Info
Start Date :
June 8 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 8 2024
Estimated Enrollment :
31 Patients enrolled
Trial Details
Trial ID
NCT05404867
Start Date
June 8 2022
End Date
January 8 2024
Last Update
January 9 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, United States, 03756