Status:
ACTIVE_NOT_RECRUITING
A Clinical Trial to Investigate the Long-term Safety and Tolerability, Efficacy, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of ARGX-117 in Adults With Multifocal Motor Neuropathy
Lead Sponsor:
argenx
Conditions:
Multifocal Motor Neuropathy (MMN)
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
This trial is an extension of the antecedent trial ARGX-117-2002. It is a multicenter trial that has been designed to evaluate the long-term safety and tolerability, efficacy, immunogenicity, Pharmaco...
Eligibility Criteria
Inclusion
- Capable of providing signed informed consent and complying with protocol requirements. Participants must be able to read and write.
- Must have completed the double-blinded treatment period of the ARGX-117-2002 trial and considered to be eligible for treatment with ARGX-117.
Exclusion
- Clinically significant uncontrolled active or chronic bacterial, viral, or fungal infection.
- Clinical evidence of other significant serious diseases, have had a recent major surgery, or who have any other condition, in the opinion of the investigator, that could confound the results of the trial or put the participant at undue risk.
- Currently participating in another interventional clinical study.
- Pregnant or lactating or intend to become pregnant during the trial or within 15 months after last dose of the study drug.
Key Trial Info
Start Date :
January 18 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 30 2029
Estimated Enrollment :
51 Patients enrolled
Trial Details
Trial ID
NCT05405361
Start Date
January 18 2023
End Date
September 30 2029
Last Update
May 13 2025
Active Locations (27)
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1
HonorHealth Neurology
Scottsdale, Arizona, United States, 85251
2
NorthShore University HealthSystem
Glenview, Illinois, United States, 60026
3
University of Minnesota
Minneapolis, Minnesota, United States, 55414
4
The Cleveland Clinic Foundation
Cleveland, Ohio, United States, 44195