Status:
RECRUITING
Stereotactic Multiple Fraction Radiotherapy for Non-spine Bone Metastases
Lead Sponsor:
Kantonsspital Winterthur KSW
Collaborating Sponsors:
Krebsforschung Schweiz, Bern, Switzerland
Conditions:
Radiation Therapy
Bone Metastases
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
To investigate, whether multi-fraction stereotactic body radiation therapy (SBRT) within 3 treatment fractions is non-inferior to the current standard of care of 5 fraction SBRT regarding pain respons...
Eligibility Criteria
Inclusion
- Personally signed and dated written informed consent,
- Histological diagnosis of malignancy,
- Histologically or radiologically diagnosed bone metastasis,
- Age ≥ 18 years
- Pain or under pain control medication
Exclusion
- Pregnant or lactating women,
- Women of childbearing potential or sexually active males not willing to use effective contraception while on treatment and 3 months after the end of treatment,
- Inability to follow the procedures of the study, e.g., due to language problems, psychological disorders, dementia, etc.,
- Prior radiotherapy to the intended treatment site,
- Lesions \> 5cm in maximum diameter,
- Prior treatment with radioactive isotopes within 30 days of randomisation,
- Spinal column, hands, feet, or head as intended treatment site,- Fracture at the intended treatment site,
- Surgery required or previous surgery at the intended treatment site
- Instability of the intended treatment site.
Key Trial Info
Start Date :
June 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 31 2026
Estimated Enrollment :
162 Patients enrolled
Trial Details
Trial ID
NCT05406063
Start Date
June 1 2022
End Date
May 31 2026
Last Update
May 22 2025
Active Locations (2)
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1
Kantonsspital Winterthur
Winterthur, Canton of Zurich, Switzerland, 8401
2
University Hospital Bern
Bern, Switzerland, 3010