Status:
WITHDRAWN
Clinical Outcomes of Persistent Atrial Fibrillation Ablation Using Ablation Index-guided Radiofrequency Catheter Ablation in Patients With Continuous Monitoring
Lead Sponsor:
St. Louis University
Conditions:
Persistent Atrial Fibrillation
Eligibility:
All Genders
18+ years
Brief Summary
Atrial fibrillation (AF) is the commonest condition affecting the rhythm of the heart. Tablets to try to normalize the heart rhythm rarely work well. As a result, doctors have devised a treatment call...
Detailed Description
Single-center, prospective cohort study including patients with persistent AF (PeAF). Primary Hypothesis: Single AF ablation procedure that includes PVI achieved with point-by-point Wide Area Circum...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Aged over 18 years
- Persistent AF defined according to the 2017 HRS/EHRA/ECAS/APHRS/SOLAECE Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation, as AF episode that lasts longer than 7 days. (Calkins et al., 2017)
- Symptomatic despite drug treatment.
- Due to undergo AF ablation.
- Exclusion criteria:
- Inability or unwillingness to receive oral anticoagulation with a Vitamin K antagonist (VKA) or non-VKA (NOAC) agent
- Previous catheter or surgical ablation procedure for AF
- Unwillingness or inability to complete the required follow-up arrangements
- Current pattern of paroxysmal AF
- Long standing persistent AF (continuous AF longer than 12 months before ablation)
- Prior prosthetic mitral valve replacement or severe structural cardiac abnormality
- Known infiltrative cardiomyopathy
- Known severe left ventricular systolic function (ejection fraction \<35%)
- Pregnancy
Exclusion
Key Trial Info
Start Date :
May 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 30 2025
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT05406310
Start Date
May 1 2024
End Date
June 30 2025
Last Update
July 15 2024
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