Status:
UNKNOWN
Monitorings the Physiological Mechanism of Airway Pressure Release Ventilation in ARDS Patients by EIT
Lead Sponsor:
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Conditions:
Electrical Impedance Tomography
ARDS
Eligibility:
All Genders
18-80 years
Brief Summary
Effects of airway pressure release ventilation on pulmonary ventilation, shunt and perfusion in patients with ARDS
Detailed Description
Effects of airway pressure release ventilation on respiratory mechanisms including ventilation distribution, intrapulmonary shunt and V/Q match in lungs of ARDS evaluated by EIT at different time poin...
Eligibility Criteria
Inclusion
- 18 years old \< age \< 80 years old
- Diagnosed as moderate or severe ARDS according to the Berlin 2014 definition
- Predicted APRV mechanical ventilation for more than 72 hours
Exclusion
- Excluded if any of the following exclusion criteria are met:
- APRV contraindications such as pneumothorax, severe chronic obstructive pulmonary disease, severe asthma, intracranial hypertension
- Pregnant women
- Severe cardiac dysfunction (New York Heart Association class III or IV, acute coronary syndrome or sustained ventricular tachyarrhythmia), right heart enlargement due to chronic cardiopulmonary disease, cardiogenic shock or cardiac hand
- Refractory shock
- BMI\>35
Key Trial Info
Start Date :
March 1 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2024
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT05406427
Start Date
March 1 2022
End Date
March 1 2024
Last Update
November 8 2022
Active Locations (1)
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1
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China, 430000