Status:

COMPLETED

Pharmacokinetic Study of Paracetamol UNIFLASH (125 MG/1.25 ML)

Lead Sponsor:

Unither Pharmaceuticals, France

Collaborating Sponsors:

Raptim Research

Conditions:

Acute Pain

Eligibility:

All Genders

18-45 years

Phase:

PHASE1

Brief Summary

This study aims to assess the pharmacokinetic profile of a new paracetamol formulation (paracetamol Uniflash 125mg/1.25mL) for buccal use after single dose.

Eligibility Criteria

Inclusion

  • Male and non-pregnant female human subjects, age 18 - 45 years.
  • Body Mass Index between 18.5-30 Kg / m2 .
  • Subjects with normal findings .
  • Willingness to follow the protocol requirements

Exclusion

  • History of allergy or hypersensitivity intolerance to paracetamol and ethanol
  • Significant history or current evidence of malignancy or chronic - infectious, cardiovascular, renal, hepatic, ophthalmic, pulmonary, neurological, metabolic (endocrine), hematological, gastrointestinal, dermatological, immunological or psychiatric diseases, or organ dysfunction;
  • Lactating or nursing female subjects;
  • History of difficulty in accessibility of veins in arms.

Key Trial Info

Start Date :

July 22 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 23 2022

Estimated Enrollment :

32 Patients enrolled

Trial Details

Trial ID

NCT05406752

Start Date

July 22 2022

End Date

July 23 2022

Last Update

December 13 2024

Active Locations (1)

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1

Raptim Research Pvt. Ltd.

Navi Mumbai, India, 400710